SCHEMBL30998305

SCHEMBL30998305

O=C(CBr)c1ccc(Br)cn1

nearest known ligand 0.62

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.62
KDM4E B2RXH2 1/20 0.62
GSK3B P49841 3/20 0.50
TSHR P16473 1/20 0.40
RAB9A P51151 5/20 0.38
NPC1 O15118 4/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
PTPN1 P18031 2/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
RXFP1 Q9HBX9 1/20 0.37
PLAU P00749 1/20 0.36
ADRA2A P08913 1/20 0.36
ADRA2B P18089 1/20 0.36
ADRA2C P18825 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1438181 1.00 ALDH1A1 (0.62) ALDH1A1KDM4EGSK3BTSHRRAB9A
Bromide SCHEMBL4892809 0.98 ALDH1A1 (0.60) ALDH1A1KDM4EGSK3BTSHRRAB9A
SCHEMBL12158841 0.82 ALDH1A1 (0.60) ALDH1A1KDM4EGSK3BTSHRRAB9A
SCHEMBL30504097 0.82 ALDH1A1 (0.60) ALDH1A1KDM4EGSK3BTSHRRAB9A
SCHEMBL14280836 0.82 KDM4E (0.60) ALDH1A1KDM4ETSHRRAB9ANPC1
SCHEMBL24863986 0.82 ALDH1A1 (0.60) ALDH1A1KDM4ETSHRRAB9ANPC1
SCHEMBL15856199 0.82 ALDH1A1 (0.60) ALDH1A1KDM4EGSK3BTSHRRAB9A
SCHEMBL16601084 0.80 PTPN1 (0.50) ALDH1A1KDM4EGSK3BPTPN1
SCHEMBL31584941 0.79 ALDH1A1 (0.61) ALDH1A1KDM4ETSHRRAB9ANPC1
SCHEMBL12461455 0.79 ALDH1A1 (0.56) ALDH1A1KDM4ETSHRRAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119731169-A Sodium channel regulator and application thereof 上海汇伦医药股份有限公司 2025-03-28 CN disclosed
WO-2024153173-A1 AROMATIC ACETYLENE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF 浙江海正药业股份有限公司 2024-07-25 WO disclosed