⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24031303 | 0.91 | — | — | |
| SCHEMBL16616355 | 0.80 | OPRM1 (0.37) | — | |
| SCHEMBL23387970 | 0.78 | — | — | |
| SCHEMBL31731968 | 0.72 | — | — | |
| SCHEMBL4730752 | 0.71 | — | — | |
| SCHEMBL4729117 | 0.70 | — | — | |
| SCHEMBL13893630 | 0.69 | OPRM1 (0.32) | — | |
| SCHEMBL15400313 | 0.67 | — | — | |
| SCHEMBL16653850 | 0.65 | — | — | |
| SCHEMBL31732144 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112939967-B | Pyrazolo [1,5-a ] pyridine compound, and preparation method and application thereof | 深圳众格生物科技有限公司 | 2024-08-27 | — | — | CN | disclosed |
| CN-114787161-B | Pyrazolo [1,5-a ] pyridine compound, and preparation method and application thereof | 深圳众格生物科技有限公司 | 2024-08-02 | — | — | CN | disclosed |