Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | KDM4A | O75164 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16325116 | 0.93 | SMN1; SMN2 (0.71) | SMN1; SMN2HTTCYP3A4CYP2B6KMT2A | |
| SCHEMBL16325115 | 0.93 | SMN1; SMN2 (0.71) | SMN1; SMN2HTTCYP3A4CYP2B6KMT2A | |
| SCHEMBL30998844 | 0.85 | KMT2A (0.48) | SMN1; SMN2HTTCYP3A4CYP2B6KMT2A | |
| SCHEMBL16324487 | 0.85 | SMN1; SMN2 (0.64) | SMN1; SMN2HTTCYP3A4CYP2B6KMT2A | |
| SCHEMBL16324490 | 0.85 | SMN1; SMN2 (0.64) | SMN1; SMN2HTTCYP3A4CYP2B6KMT2A | |
| SCHEMBL16324039 | 0.84 | SMN1; SMN2 (0.69) | SMN1; SMN2HTTCYP3A4CYP2B6KMT2A | |
| SCHEMBL16324040 | 0.84 | SMN1; SMN2 (0.69) | SMN1; SMN2HTTCYP3A4CYP2B6KMT2A | |
| SCHEMBL16321646 | 0.82 | SMN1; SMN2 (0.53) | SMN1; SMN2HTTCYP3A4CYP2B6KMT2A | |
| SCHEMBL16321643 | 0.82 | SMN1; SMN2 (0.53) | SMN1; SMN2HTTCYP3A4CYP2B6KMT2A | |
| SCHEMBL16324209 | 0.82 | SMN1; SMN2 (0.63) | SMN1; SMN2HTTCYP3A4CYP2B6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118373777-A | Pyrimidine diketone derivative and preparation method and application thereof | 河北科技大学 | 2024-07-23 | — | — | CN | disclosed |