Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | CNR2 | P34972 | 5/20 | 0.48 |
| ▸ | CNR1 | P21554 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30998763 | 0.85 | SMN1; SMN2 (0.62) | KMT2ASMN1; SMN2HTTCYP3A4CYP2B6 | |
| SCHEMBL16321643 | 0.80 | SMN1; SMN2 (0.53) | KMT2ASMN1; SMN2HTTCYP3A4CYP2B6 | |
| SCHEMBL16321646 | 0.80 | SMN1; SMN2 (0.53) | KMT2ASMN1; SMN2HTTCYP3A4CYP2B6 | |
| SCHEMBL16325115 | 0.78 | SMN1; SMN2 (0.71) | KMT2ASMN1; SMN2HTTCYP3A4CYP2B6 | |
| SCHEMBL16325116 | 0.78 | SMN1; SMN2 (0.71) | KMT2ASMN1; SMN2HTTCYP3A4CYP2B6 | |
| SCHEMBL30998786 | 0.77 | SMN1; SMN2 (0.45) | CNR2CNR1SMN1; SMN2HTTEGFR | |
| SCHEMBL16320887 | 0.74 | CYP3A4 (0.76) | SMN1; SMN2HTTEGFRCYP3A4CYP2B6 | |
| SCHEMBL16320885 | 0.74 | CYP3A4 (0.76) | SMN1; SMN2HTTEGFRCYP3A4CYP2B6 | |
| SCHEMBL30998829 | 0.73 | HTT (0.43) | SMN1; SMN2HTTCYP3A4CYP2B6 | |
| SCHEMBL16322889 | 0.73 | SMN1; SMN2 (0.47) | KMT2ASMN1; SMN2HTTCYP3A4CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118373777-A | Pyrimidine diketone derivative and preparation method and application thereof | 河北科技大学 | 2024-07-23 | — | — | CN | disclosed |