SCHEMBL30999610

CSCC[C@H](NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(C)=O)C(C)C)C(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1cccc(Br)c1)C(N)=O

nearest known ligand 0.62

Predicted protein targets (top 3)

	gene	UniProt	supporting neighbours	confidence
▸	CCKBR	P32239	8/20	0.62

▸	IL23R	Q5VWK5	8/20	0.59

▸	GLP1R	P43220	1/20	0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30999605	0.87	RXFP1 (0.69)	CCKBRGLP1R
SCHEMBL30436108	0.86	GLP1R (0.62)	CCKBRIL23RGLP1R
SCHEMBL30380786	0.86	PTH1R (0.60)	CCKBRIL23RGLP1R
SCHEMBL30380861	0.85	GLP1R (0.59)	CCKBRIL23RGLP1R
SCHEMBL30999638	0.85	CCKBR (0.64)	CCKBRGLP1R
SCHEMBL30358216	0.85	GLP1R (0.72)	CCKBRGLP1R
SCHEMBL30999636	0.84	IL23R (0.64)	CCKBRIL23RGLP1R
SCHEMBL29533287	0.83	CCKBR (0.60)	CCKBRIL23RGLP1R
SCHEMBL1352119	0.83	RXFP1 (0.72)	CCKBRIL23RGLP1R
SCHEMBL30495731	0.83	GLP1R (0.64)	CCKBRIL23RGLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4421082-A1	POLYPEPTIDE AND APPLICATION THEREOF AS CCK RECEPTOR AGONIST/ANTAGONIST	Centre for Regenerative Medicine and Health, Hong Kong Institute of Science & Innovation, Chinese Academy of Sciences Limited (HK)	2024-08-28	—	—	EP	disclosed