Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 8/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17810271 | 0.81 | DGAT1 (0.42) | DGAT1BRD4NPC1 | |
| SCHEMBL16534784 | 0.80 | DGAT1 (0.40) | DGAT1BRD4NPC1KDM4EALDH1A1 | |
| SCHEMBL16535653 | 0.78 | DGAT1 (0.40) | DGAT1NPC1ALDH1A1HTTL3MBTL1 | |
| SCHEMBL16535654 | 0.78 | DGAT1 (0.40) | DGAT1NPC1ALDH1A1HTTL3MBTL1 | |
| SCHEMBL16534722 | 0.78 | DGAT1 (0.40) | DGAT1BRD4ALDH1A1 | |
| SCHEMBL16535104 | 0.76 | DGAT1 (0.39) | DGAT1ALDH1A1 | |
| SCHEMBL21645879 | 0.75 | DGAT1 (0.40) | DGAT1BRD4NPC1MAPT | |
| SCHEMBL3083653 | 0.74 | DGAT1 (0.39) | DGAT1BRD4NPC1MAPT | |
| SCHEMBL22075645 | 0.71 | DGAT1 (0.36) | DGAT1NPC1KDM4EMAPT | |
| SCHEMBL20752448 | 0.70 | CYP1A2 (0.43) | BRD4NPC1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118055926-A | ROCK2 inhibitors and uses thereof | 哈佛大学的校长及成员们 | 2024-05-17 | — | — | CN | disclosed |