Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 9/20 | 0.74 |
| ▸ | GSK3A | P49840 | 1/20 | 0.48 |
| ▸ | SRD5A1 | P18405 | 6/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30999966 | 1.00 | GSK3B (0.74) | GSK3BGSK3ASRD5A1ROCK1NOTUM | |
| SCHEMBL31000001 | 0.92 | GSK3B (0.83) | GSK3BGSK3ASRD5A1ROCK1NOTUM | |
| SCHEMBL30999951 | 0.85 | GSK3B (1.00) | GSK3BGSK3ASRD5A1MAPT | |
| SCHEMBL30999985 | 0.84 | GSK3B (0.81) | GSK3BGSK3ASRD5A1MAPT | |
| SCHEMBL30999936 | 0.75 | GSK3B (0.76) | GSK3BGSK3ASRD5A1 | |
| SCHEMBL14294210 | 0.72 | SRD5A1 (0.51) | GSK3BSRD5A1ROCK1NOTUMHSD17B3 | |
| SCHEMBL10621418 | 0.67 | ROCK1 (0.52) | GSK3BSRD5A1ROCK1NOTUMHSD17B3 | |
| SCHEMBL3816794 | 0.67 | GSK3B (0.67) | GSK3BGSK3A | |
| SCHEMBL11445576 | 0.67 | MAPK1 (0.53) | GSK3BSRD5A1ROCK1NOTUMMAPT | |
| SCHEMBL6586836 | 0.67 | GSK3B (1.00) | GSK3BGSK3AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024163852-A1 | HISTIDINE KINASE INHIBITORS AS ANTIBACTERIAL AGENTS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2024-08-08 | — | — | WO | disclosed |