Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 3/20 | 0.43 |
| ▸ | CCND1 | P24385 | 3/20 | 0.43 |
| ▸ | CCND3 | P30281 | 3/20 | 0.43 |
| ▸ | CDK6 | Q00534 | 3/20 | 0.43 |
| ▸ | EIF2AK4 | Q9P2K8 | 6/20 | 0.35 |
| ▸ | DYRK2 | Q92630 | 5/20 | 0.34 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31000156 | 0.84 | CDK4 (0.45) | CDK4CCND1CCND3CDK6EIF2AK4 | |
| SCHEMBL31000140 | 0.83 | CDK4 (0.44) | CDK4CCND1CCND3CDK6EIF2AK4 | |
| SCHEMBL31000209 | 0.82 | CDK4 (0.43) | CDK4CCND1CCND3CDK6DYRK2 | |
| SCHEMBL31000199 | 0.80 | CDK4 (0.40) | CDK4CCND1CCND3CDK6EIF2AK4 | |
| SCHEMBL31000072 | 0.78 | CDK4 (0.45) | CDK4CCND1CCND3CDK6DYRK2 | |
| SCHEMBL31000086 | 0.77 | CDK7 (0.41) | CDK4CCND1CCND3CDK6CDK2 | |
| SCHEMBL24574392 | 0.76 | EIF2AK4 (0.35) | CDK4CCND1CCND3CDK6EIF2AK4 | |
| SCHEMBL31000311 | 0.76 | CDK4 (0.45) | CDK4CCND1CCND3CDK6DYRK2 | |
| SCHEMBL31000233 | 0.76 | CDK4 (0.45) | CDK4CCND1CCND3CDK6DYRK2 | |
| SCHEMBL29748726 | 0.76 | EIF2AK4 (0.35) | CDK4CCND1CCND3CDK6EIF2AK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658659-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | Children's Hospital Medical Center (US) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024163764-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2024-08-08 | — | — | WO | disclosed |