Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 2/20 | 0.44 |
| ▸ | CCND1 | P24385 | 2/20 | 0.44 |
| ▸ | CCND3 | P30281 | 2/20 | 0.44 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.44 |
| ▸ | EIF2AK4 | Q9P2K8 | 11/20 | 0.43 |
| ▸ | IGF1R | P08069 | 2/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | DYRK2 | Q92630 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31000156 | 0.94 | CDK4 (0.45) | CDK4CCND1CCND3CDK6EIF2AK4 | |
| SCHEMBL25338902 | 0.85 | EIF2AK4 (0.43) | EIF2AK4 | |
| SCHEMBL31000153 | 0.83 | CDK4 (0.43) | CDK4CCND1CCND3CDK6EIF2AK4 | |
| SCHEMBL31000154 | 0.82 | CDK7 (0.41) | EIF2AK4CDK2 | |
| SCHEMBL31000199 | 0.79 | CDK4 (0.40) | CDK4CCND1CCND3CDK6EIF2AK4 | |
| SCHEMBL31000111 | 0.78 | CDK4 (0.40) | CDK4CCND1CCND3CDK6EIF2AK4 | |
| SCHEMBL31501015 | 0.78 | CDK2 (0.43) | CDK4CCND1CCND3CDK6IGF1R | |
| SCHEMBL24231561 | 0.78 | EIF2AK4 (0.41) | EIF2AK4 | |
| SCHEMBL31000072 | 0.77 | CDK4 (0.45) | CDK4CCND1CCND3CDK6IGF1R | |
| SCHEMBL24231691 | 0.77 | SYK (0.43) | EIF2AK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658659-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | Children's Hospital Medical Center (US) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024163764-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2024-08-08 | — | — | WO | disclosed |