Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 8/20 | 0.39 |
| ▸ | KMO | O15229 | 4/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.35 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.35 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31000241 | 0.86 | PDE4D (0.34) | PDE4DDYRK1ADYRK3DYRK2CCNT1 | |
| SCHEMBL31000221 | 0.85 | DYRK1A (0.38) | PDE4DDYRK1ADYRK3DYRK2CCNT1 | |
| SCHEMBL31000227 | 0.80 | KMO (0.35) | PDE4DKMO | |
| SCHEMBL31000324 | 0.79 | DYRK1A (0.40) | PDE4DDYRK1ADYRK3DYRK2CCNT1 | |
| SCHEMBL31000240 | 0.78 | DYRK1A (0.39) | PDE4DDYRK1ADYRK3DYRK2CCNT1 | |
| SCHEMBL31000222 | 0.77 | PDE4D (0.33) | PDE4DIRAK4FYN | |
| SCHEMBL31000214 | 0.77 | MAPK8 (0.36) | IRAK4CCNT1CDK9DYRK1BPIM1 | |
| SCHEMBL31000208 | 0.76 | DYRK1A (0.40) | PDE4DIRAK4DYRK1ADYRK3DYRK2 | |
| SCHEMBL31000343 | 0.76 | DYRK1A (0.38) | PDE4DDYRK1ADYRK3DYRK2CCNT1 | |
| SCHEMBL31000298 | 0.73 | TYRO3 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658659-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | Children's Hospital Medical Center (US) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024163764-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2024-08-08 | — | — | WO | disclosed |