Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 16/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30698336 | 0.84 | SYK (0.38) | RIPK1USP30TBK1CFTRMAPT | |
| SCHEMBL24542620 | 0.83 | FLT3 (0.40) | USP30CFTRMAPT | |
| SCHEMBL31000281 | 0.82 | DYRK1A (0.37) | — | |
| SCHEMBL31000196 | 0.81 | CFTR (0.39) | TBK1CFTR | |
| SCHEMBL31000124 | 0.81 | PDE4B (0.36) | CFTRMAPT | |
| SCHEMBL26661906 | 0.80 | CFTR (0.35) | RIPK1TBK1CFTR | |
| SCHEMBL24975704 | 0.80 | CFTR (0.35) | RIPK1TBK1CFTR | |
| SCHEMBL31000136 | 0.80 | PREP (0.34) | MAPT | |
| SCHEMBL31000174 | 0.79 | CDK4 (0.44) | TBK1CFTR | |
| SCHEMBL24975903 | 0.79 | USP30 (0.36) | RIPK1USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658659-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | Children's Hospital Medical Center (US) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024163764-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2024-08-08 | — | — | WO | disclosed |