Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK7 | P50613 | 4/20 | 0.50 |
| ▸ | CCNH | P51946 | 4/20 | 0.50 |
| ▸ | MNAT1 | P51948 | 4/20 | 0.50 |
| ▸ | CCNK | O75909 | 4/20 | 0.50 |
| ▸ | CDK12 | Q9NYV4 | 4/20 | 0.50 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.50 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.50 |
| ▸ | CDK2 | P24941 | 3/20 | 0.50 |
| ▸ | CDK9 | P50750 | 3/20 | 0.50 |
| ▸ | IGF1R | P08069 | 13/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | CCND3 | P30281 | 1/20 | 0.37 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.37 |
| ▸ | NRAS | P01111 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31000133 | 0.94 | CDK7 (0.42) | CDK7CCNHMNAT1CCNKCDK12 | |
| SCHEMBL31000198 | 0.91 | CDK7 (0.41) | CDK7CCNHMNAT1CCNKCDK12 | |
| SCHEMBL31000232 | 0.85 | FLT3 (0.39) | CDK7CCNHMNAT1CCNKCDK12 | |
| SCHEMBL31000215 | 0.85 | FLT3 (0.39) | CDK7CCNHMNAT1CCNKCDK12 | |
| SCHEMBL31000224 | 0.85 | FLT3 (0.39) | CDK7CCNHMNAT1CCNKCDK12 | |
| SCHEMBL24975698 | 0.85 | FLT3 (0.41) | CDK7CCNHMNAT1CCNKCDK12 | |
| SCHEMBL31557816 | 0.85 | FLT3 (0.41) | CDK7CCNHMNAT1CCNKCDK12 | |
| SCHEMBL27362507 | 0.85 | FLT3 (0.41) | CDK7CCNHMNAT1CCNKCDK12 | |
| SCHEMBL31000190 | 0.84 | FLT3 (0.39) | CDK7CCNHMNAT1CCNKCDK12 | |
| SCHEMBL27327896 | 0.84 | NRAS (0.42) | CDK7CCNHMNAT1CCNKCDK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658659-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | Children's Hospital Medical Center (US) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024163764-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2024-08-08 | — | — | WO | disclosed |