Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.50 |
| ▸ | GSTK1 | Q9Y2Q3 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11279244 | 1.00 | LMNA (0.52) | LMNATSHRNFKB1PMP22FFAR4 | |
| SCHEMBL11283608 | 1.00 | LMNA (0.52) | LMNATSHRNFKB1PMP22FFAR4 | |
| SCHEMBL10944728 | 1.00 | LMNA (0.52) | LMNATSHRNFKB1PMP22FFAR4 | |
| Adipic Acid SCHEMBL7050293 | 1.00 | LMNA (0.52) | LMNATSHRNFKB1PMP22FFAR4 | |
| SCHEMBL15153687 | 0.98 | LMNA (0.50) | LMNATSHRNFKB1PMP22FFAR4 | |
| SCHEMBL2473072 | 0.98 | LMNA (0.50) | LMNATSHRNFKB1PMP22FFAR4 | |
| SCHEMBL10618648 | 0.94 | FFAR4 (0.61) | LMNATSHRNFKB1PMP22FFAR4 | |
| SCHEMBL12355088 | 0.91 | CAMK2A (0.46) | LMNATSHRNFKB1PMP22FFAR4 | |
| SCHEMBL1244924 | 0.91 | CAMK2A (0.46) | LMNATSHRNFKB1PMP22FFAR4 | |
| Sebacic Acid SCHEMBL10010951 | 0.91 | TSHR (0.63) | LMNATSHRNFKB1PMP22FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10308920-B2 | Hydrolases, nucleic acids encoding them and methods for making and using them | DSM IP ASSETS B.V. (NL) | 2019-06-04 | — | — | US | disclosed |
| EP-3299465-A1 | HYDROLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | DSM IP Assets B.V. (NL) | 2018-03-28 | — | — | EP | disclosed |
| EP-2853593-B1 | Hydrolases, nucleic acids encoding them and mehods for making and using them | DSM IP ASSETS BV (NL) | 2017-10-04 | — | — | EP | disclosed |
| US-9499844-B2 | Compositions and methods for making and modifying oils | DSM IP ASSETS B.V. (NL) | 2016-11-22 | — | — | US | disclosed |
| US-20160168604-A1 | COMPOSITIONS AND METHODS FOR MAKING AND MODIFYING OILS | DSM IP ASSETS B.V. (NL) | 2016-06-16 | — | — | US | disclosed |
| US-20160060609-A1 | HYDROLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | DSM IP ASSETS B.V. (NL) | 2016-03-03 | — | — | US | disclosed |
| US-9243267-B2 | Compositions and methods for making and modifying oils | DSM IP ASSETS B.V. (NL) | 2016-01-26 | — | — | US | disclosed |
| US-20150344918-A1 | COMPOSITIONS AND METHODS FOR MAKING AND MODIFYING OILS | DSM IP ASSETS B.V. (NL) | 2015-12-03 | — | — | US | disclosed |
| US-9193962-B2 | Hydrolases, nucleic acids encoding them and methods for making and using them | DSM IP ASSETS B.V. (NL) | 2015-11-24 | — | — | US | disclosed |
| US-9034612-B2 | Compositions and methods for making and modifying oils | DSM IP ASSETS, B.V. (NL) | 2015-05-19 | — | — | US | disclosed |
| EP-2853593-A1 | Hydrolases, nucleic acids encoding them and mehods for making and using them | DSM IP Assets B.V. (NL) | 2015-04-01 | — | — | EP | disclosed |
| US-20140193866-A1 | Compositions and Methods for Making and Modifying Oils | DSM IP ASSETS B.V. (NL) | 2014-07-10 | — | — | US | disclosed |
| US-20140128590-A1 | HYDROLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | DSM IP ASSETS B.V. (NL) | 2014-05-08 | — | — | US | disclosed |
| US-8557551-B2 | Compositions and methods for making and modifying oils | DSM IP ASSETS B.V. (NL) | 2013-10-15 | — | — | US | disclosed |
| US-8298799-B2 | Hydrolases, nucleic acids encoding them and methods for making and using them | DSM IP ASSETS B. V. (NL) | 2012-10-30 | — | — | US | disclosed |
| EP-2216403-A2 | Esterases and related nucleic acids and methods | Verenium Corporation (US) | 2010-08-11 | — | — | EP | disclosed |
| US-20090324574-A1 | Esterases and Related Nucleic Acids and Methods | VERENIUM CORPORATION (US) | 2009-12-31 | — | — | US | disclosed |
| US-20090297495-A1 | HYDROLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR IMPROVING PAPER STRENGTH | VERENIUM CORPORATION | 2009-12-03 | — | — | US | disclosed |
| US-20080305531-A1 | Making an oil or lipid low in a particular fatty acid species for example, low linoleic oils, low palmitic oils using an enzyme that will selectively hydrolyze said fatty acid; paints, synthetic fuels, synthetic lubricant or fuel fat, confectionary fats | VERENIUM CORPORATION (US) | 2008-12-11 | — | — | US | disclosed |
| US-20070202566-A1 | Hydrolases, Nucleic Acids Encoding Them And Methods For Making And Using Them | DSM IP ASSETS B.V. (NL) | 2007-08-30 | — | — | US | disclosed |