Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 4/20 | 0.52 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.52 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.52 |
| ▸ | PI4KA | P42356 | 1/20 | 0.48 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.48 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.48 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.42 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.40 |
| ▸ | AMD1 | P17707 | 2/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.39 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.39 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31001604 | 0.94 | P2RX3 (0.51) | P2RX3P2RX1P2RX4PI4KAPI4K2B | |
| SCHEMBL31001618 | 0.93 | P2RX3 (0.50) | P2RX3P2RX1P2RX4PI4KAPI4K2B | |
| SCHEMBL31001565 | 0.93 | P2RX3 (0.49) | P2RX3P2RX1P2RX4PI4KAPI4K2B | |
| SCHEMBL31001642 | 0.93 | P2RX3 (0.49) | P2RX3P2RX1P2RX4PI4KAPI4K2B | |
| SCHEMBL31001554 | 0.90 | P2RX3 (0.51) | P2RX3P2RX1P2RX4PI4KAPI4K2B | |
| SCHEMBL31001514 | 0.88 | P2RX3 (0.54) | P2RX3P2RX1P2RX4PI4KAPI4K2B | |
| SCHEMBL31001625 | 0.85 | DOT1L (0.48) | P2RX3P2RX1P2RX4PI4KAPI4K2B | |
| SCHEMBL31001611 | 0.85 | DOT1L (0.48) | P2RX3P2RX1P2RX4PI4KAPI4K2B | |
| SCHEMBL31001586 | 0.84 | DOT1L (0.48) | P2RX3P2RX1P2RX4PI4KAPI4K2B | |
| SCHEMBL31001588 | 0.83 | P2RX3 (0.54) | P2RX3P2RX1P2RX4PI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024177959-A1 | SMALL MOLECULE TRACER LIGANDS FOR AMINOACYL-TRNA SYNTHETASE ASSAYS | THE GENERAL HOSPITAL CORPORATION (US) | 2024-08-29 | — | — | WO | disclosed |