Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31192971 | 1.00 | IRAK4 (0.32) | IRAK4PDE3BPDE3A | |
| SCHEMBL31192905 | 0.77 | ADORA1 (0.37) | IRAK4 | |
| SCHEMBL31160303 | 0.77 | IRAK4 (0.39) | IRAK4PDE3BPDE3A | |
| SCHEMBL14941607 | 0.76 | AOC1 (0.34) | — | |
| SCHEMBL31002370 | 0.73 | CHRM2 (0.34) | PDE3BPDE3A | |
| SCHEMBL30911550 | 0.73 | CHRM2 (0.34) | PDE3BPDE3A | |
| SCHEMBL13733989 | 0.73 | CYP1A2 (0.32) | — | |
| SCHEMBL15110157 | 0.73 | KAT2B (0.37) | — | |
| SCHEMBL30627275 | 0.73 | KAT2B (0.37) | — | |
| SCHEMBL30911776 | 0.71 | TDP1 (0.36) | PDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658662-A1 | MACROCYCLIC AMINOPYRIDINE COMPOUNDS AS EGFR INHIBITORS | Yuhan Corporation (KR) | 2025-12-10 | — | — | EP | disclosed |
| EP-4655304-A1 | MACROCYCLIC AMINOPYRIDINE COMPOUNDS AS EGFR INHIBITORS | Yuhan Corporation (KR) | 2025-12-03 | — | — | EP | disclosed |
| WO-2024177360-A1 | MACROCYCLIC AMINOPYRIDINE COMPOUNDS AS EGFR INHIBITORS | YUHAN CORPORATION (KR) | 2024-08-29 | — | — | WO | disclosed |
| WO-2024177362-A1 | MACROCYCLIC AMINOPYRIDINE COMPOUNDS AS EGFR INHIBITORS | YUHAN CORPORATION (KR) | 2024-08-29 | — | — | WO | disclosed |