1,6-Hexanediol

1,6-Hexanediol

SCHEMBL3100208

O=C(Cl)Cl.OCCCCCCO

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.53
FFAR1 O14842 1/20 0.53
FFAR4 Q5NUL3 1/20 0.53
ALDH1A1 P00352 3/20 0.44
TSHR P16473 3/20 0.44
LMNA P02545 2/20 0.44
HSD17B10 Q99714 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
CAMK2A Q9UQM7 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
KDM4E B2RXH2 1/20 0.42
FNTA P49354 1/20 0.39
FNTB P49356 1/20 0.39
CYP4F2 P78329 2/20 0.34
CYP4A11 Q02928 2/20 0.34
GAA P10253 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
EPHX2 P34913 2/20 0.33
MIF P14174 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,4-Butanediol SCHEMBL10945004 0.96 GPR84 (0.47) GPR84FFAR1FFAR4ALDH1A1TSHR
1,6-Hexanediol SCHEMBL5836918 0.89 GPR84 (0.58) GPR84FFAR1FFAR4ALDH1A1TSHR
1,4-Butanediol SCHEMBL5836779 0.85 GPR84 (0.53) GPR84FFAR1FFAR4ALDH1A1TSHR
1,4-Butanediol SCHEMBL9581258 0.85 GPR84 (0.53) GPR84FFAR1FFAR4ALDH1A1TSHR
SCHEMBL202630 0.81
SCHEMBL21295305 0.81 TSHR (0.59) GPR84FFAR1FFAR4ALDH1A1TSHR
1,6-Hexanediol SCHEMBL29109662 0.80 GPR84 (0.65) GPR84FFAR1FFAR4ALDH1A1TSHR
1,6-Hexanediol SCHEMBL28984424 0.80 GPR84 (0.65) GPR84FFAR1FFAR4ALDH1A1TSHR
1,5-Pentanediol SCHEMBL29150346 0.80 GPR84 (0.65) GPR84FFAR1FFAR4ALDH1A1TSHR
1,6-Hexanediol SCHEMBL6707356 0.80 GPR84 (0.65) GPR84FFAR1FFAR4ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7098274-B2 Compositions for golf equipment ACUSHNET COMPANY (US) 2006-08-29 US claimed
US-20050004325-A1 Compositions for golf equipment JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-01-06 US claimed
US-20100255934-A1 COMPOSITIONS FOR GOLF EQUIPMENT ACUSHNET COMPANY 2010-10-07 US disclosed
US-7709590-B2 Compositions for golf equipment ACUSHNET COMPANY (US) 2010-05-04 US disclosed
US-7550549-B2 Compositions for golf equipment ACUSHNET COMPANY (US) 2009-06-23 US disclosed
US-20080188326-A1 Compositions for Golf Equipment ACUSHNET COMPANY 2008-08-07 US disclosed
US-7378483-B2 Compositions for golf equipment ACUSHNET COMPANY (US) 2008-05-27 US disclosed
US-20080064527-A1 Compositions for golf equipment JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2008-03-13 US disclosed
US-7276570-B2 Compositions for golf equipment ACUSHNET COMPANY (US) 2007-10-02 US disclosed
US-7265195-B2 Compositions for golf equipment ACUSHNET COMPANY (US) 2007-09-04 US disclosed
US-7256249-B2 Compositions for golf equipment ACUSHNET COMPANY (US) 2007-08-14 US disclosed
US-20040220356-A1 Compositions for golf equipment JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-11-04 US disclosed
US-20040220378-A1 Compositions for golf equipment JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-11-04 US disclosed
US-20040220377-A1 Compositions for golf equipment JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-11-04 US disclosed
US-20040220376-A1 Compositions for golf equipment JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-11-04 US disclosed
US-20040220373-A1 Compositions for golf equipment JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-11-04 US disclosed
US-20040220357-A1 Compositions for golf equipment JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-11-04 US disclosed
US-20040220371-A1 Compositions for golf equipment JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-11-04 US disclosed
US-20040220375-A1 Compositions for golf equipment JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-11-04 US disclosed
US-5621065-A Polycarbonate diols, their preparation and use as starting products for polyurethane plastics BAYER AKTIENGESELLSCHIFT (DE) 1997-04-15 US disclosed