Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.34 |
| ▸ | OGA | O60502 | 2/20 | 0.34 |
| ▸ | SMO | Q99835 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SORD | Q00796 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PLG | P00747 | 1/20 | 0.30 |
| ▸ | PLAU | P00749 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12885846 | 1.00 | ESR1 (0.43) | ESR1ESR2PPARGUGT2B7OGA | |
| SCHEMBL2604908 | 0.83 | ESR1 (0.42) | ESR1ESR2LMNASMN1; SMN2RXRA | |
| SCHEMBL30697150 | 0.82 | ESR1 (0.50) | ESR1ESR2PPARGUGT2B7OGA | |
| SCHEMBL14645814 | 0.80 | ESR1 (0.40) | ESR1ESR2 | |
| SCHEMBL3266864 | 0.80 | ESR1 (0.43) | ESR1ESR2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL14480080 | 0.80 | ESR1 (0.40) | ESR1ESR2 | |
| SCHEMBL27966461 | 0.79 | ESR1 (0.40) | ESR1ESR2ALDH1A1LMNA | |
| SCHEMBL31003309 | 0.79 | ESR1 (0.44) | ESR1ESR2PPARGUGT2B7OGA | |
| SCHEMBL16647732 | 0.78 | MBOAT4 (0.42) | ESR1ESR2LMNARXRAGRIN1 | |
| SCHEMBL23114333 | 0.77 | ESR1 (0.38) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658656-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES | Beone Medicines I GmbH (CH) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024160276-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES | BEIGENE, LTD. (KY) | 2024-08-08 | — | — | WO | disclosed |