SCHEMBL3100326

SCHEMBL3100326

O=C(O)c1ccc2c(c1)-c1ccccc1C2=O

nearest known ligand 0.92

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 3/20 0.92
TTR P02766 7/20 0.89
CHEK1 O14757 1/20 0.65
S100A4 P26447 1/20 0.65
KMT2A Q03164 2/20 0.62
POLB P06746 1/20 0.62
MAPT P10636 2/20 0.60
MEN1 O00255 1/20 0.60
HPGD P15428 1/20 0.60
CDC25A P30304 1/20 0.60
CDC25B P30305 1/20 0.60
CTDSP1 Q9GZU7 1/20 0.60
TDP1 Q9NUW8 1/20 0.60
L3MBTL1 Q9Y468 1/20 0.60
NPC1 O15118 1/20 0.59
ALDH1A1 P00352 1/20 0.59
LMNA P02545 1/20 0.59
RAB9A P51151 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
HTR7 P34969 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4074222 0.96 PTPRC (1.00) PTPRCTTRCHEK1S100A4KMT2A
SCHEMBL292802 0.96 TTR (0.96) PTPRCTTRCHEK1S100A4KMT2A
SCHEMBL30610011 0.94 TTR (1.00) PTPRCTTRCHEK1S100A4KMT2A
SCHEMBL123492 0.94 TTR (1.00) PTPRCTTRCHEK1S100A4KMT2A
SCHEMBL11877439 0.92 TTR (0.96) PTPRCTTRCHEK1S100A4KMT2A
SCHEMBL6261915 0.92 PTPRC (1.00) PTPRCTTRCHEK1S100A4KMT2A
SCHEMBL28446002 0.92 TTR (0.96) PTPRCTTRCHEK1S100A4KMT2A
Hydrochloric Acid SCHEMBL3453762 0.92 TTR (0.96) PTPRCTTRCHEK1S100A4KMT2A
SCHEMBL29917994 0.92 TTR (0.96) PTPRCTTRCHEK1S100A4KMT2A
SCHEMBL28081049 0.92 TTR (0.96) PTPRCTTRCHEK1S100A4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023183405-A2 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS ALEXION PHARMACEUTICALS, INC. (US) 2023-09-28 WO disclosed
US-20230213863-A1 COMPOUND, RESIST UNDERLAYER FILM COMPOSITION INCLUDING SAME, AND RESIST UNDERLAYER FILM DONGJIN SEMICHEM CO., LTD. (KR) 2023-07-06 US disclosed
US-20230213863-A1 COMPOUND, RESIST UNDERLAYER FILM COMPOSITION INCLUDING SAME, AND RESIST UNDERLAYER FILM DONGJIN SEMICHEM CO., LTD. (KR) 2023-07-06 US disclosed
US-11215935-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJIFILM BUSINESS INNOVATION CORP. (JP) 2022-01-04 US disclosed
US-11169455-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJIFILM BUSINESS INNOVATION CORP. (JP) 2021-11-09 US disclosed
US-20200341392-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2020-10-29 US disclosed
US-20200341393-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2020-10-29 US disclosed
US-10754266-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2020-08-25 US disclosed
US-20200096884-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO.,LTD. (JP) 2020-03-26 US disclosed
US-7858824-B2 Aralkyltetrahydropyridines, their preparation and pharmaceutical compositions containing them SANOFI-AVENTIS (FR) 2010-12-28 US disclosed
CN-1571770-A Aralkyl-tetrahydro-pyridines, process for their preparation and pharmaceutical compositions containing them SANOFI SYNTHELABO (FR) 2005-01-26 CN disclosed
US-20050014795-A1 Aralkyl-tetrahydro-pyridines, their preparation and pharmaceutical compositions containing same SANOFI-SYNTHELABO (FR) 2005-01-20 US disclosed
US-6284365-B1 FOR CONTROLLING PHYSICAL PROPERTIES OF SURFACE AND INTERFACE OF SOLID ARTICLE SUCH AS WETTABILITY, ADHESIVE PROPERTY, SURFACE ENERGY, DISPERSABILITY, CHEMICAL RESISTANCE FUJI XEROX CO., LTD. (JP) 2001-09-04 US disclosed
US-5286603-A Substrate coated with a photopolymerizable compound containing ethylenic unsaturation, a perester photoinitiator and optionally an optical sensitizer VICKERS PLC (GB) 1994-02-15 US disclosed
US-5130227-A Multilayer light sensitive plates VICKERS PLC (GB) 1992-07-14 US disclosed
US-4946960-A ADDITION POLYMERIZATION CATALYSTS VICKERS PLC (GB) 1990-08-07 US disclosed
EP-0125140-B1 IMPROVEMENTS IN OR RELATING TO RADIATION SENSITIVE PLATES VICKERS PLC (GB) 1988-12-14 EP disclosed
EP-0125875-B1 IMPROVEMENTS IN OR RELATING TO PERESTER COMPOUNDS VICKERS PLC (GB) 1988-08-10 EP disclosed
EP-0125875-A2 Improvements in or relating to perester compounds VICKERS PLC (GB) 1984-11-21 EP disclosed
EP-0125140-A2 Improvements in or relating to radiation sensitive plates VICKERS PLC (GB) 1984-11-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050014795-A1 Aralkyl-tetrahydro-pyridines, their preparation and pharmaceutical compositions containing same CYCS, NADK, CYP2F1 PTPRC 2743/4885TTR 778/4885CHEK1 1204/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.