Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | EED | O75530 | 1/20 | 0.44 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.44 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.44 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.44 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25411425 | 1.00 | HPGD (0.48) | HPGDGPR119RECQLEPHX1ALDH1A1 | |
| SCHEMBL30478265 | 1.00 | HPGD (0.48) | HPGDGPR119RECQLEPHX1ALDH1A1 | |
| SCHEMBL14241561 | 1.00 | HPGD (0.48) | HPGDGPR119RECQLEPHX1ALDH1A1 | |
| SCHEMBL359045 | 1.00 | HPGD (0.48) | HPGDGPR119RECQLEPHX1ALDH1A1 | |
| SCHEMBL15657484 | 1.00 | HPGD (0.48) | HPGDGPR119RECQLEPHX1ALDH1A1 | |
| SCHEMBL13400338 | 0.91 | ALDH1A1 (0.51) | HPGDGPR119RECQLEPHX1ALDH1A1 | |
| SCHEMBL7934588 | 0.91 | ALDH1A1 (0.51) | HPGDGPR119RECQLEPHX1ALDH1A1 | |
| SCHEMBL29912970 | 0.91 | ALDH1A1 (0.51) | HPGDGPR119RECQLEPHX1ALDH1A1 | |
| SCHEMBL13400340 | 0.91 | ALDH1A1 (0.51) | HPGDGPR119RECQLEPHX1ALDH1A1 | |
| SCHEMBL14029688 | 0.91 | ALDH1A1 (0.51) | HPGDGPR119RECQLEPHX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024175043-A1 | PYRIDOPYRIMIDINE DERIVATIVE AND USE THEREOF | 广东东阳光药业股份有限公司 | 2024-08-29 | — | — | WO | disclosed |