Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOL1 | O14791 | 20/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22118351 | 1.00 | APOL1 (0.80) | APOL1 | |
| SCHEMBL22118385 | 0.89 | APOL1 (1.00) | APOL1 | |
| SCHEMBL22160216 | 0.89 | APOL1 (1.00) | APOL1 | |
| SCHEMBL22160166 | 0.89 | APOL1 (1.00) | APOL1 | |
| SCHEMBL22159837 | 0.88 | APOL1 (0.88) | APOL1 | |
| SCHEMBL22161403 | 0.87 | APOL1 (0.86) | APOL1 | |
| SCHEMBL22160037 | 0.86 | APOL1 (0.88) | APOL1 | |
| SCHEMBL22161322 | 0.86 | APOL1 (0.88) | APOL1 | |
| SCHEMBL22118330 | 0.85 | APOL1 (0.85) | APOL1 | |
| SCHEMBL24099480 | 0.84 | APOL1 (0.90) | APOL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3897833-B1 | INHIBITORS OF APOL1 AND METHODS OF USING SAME | VERTEX PHARMA (US) | 2026-02-04 | — | — | EP | disclosed |
| CN-113453760-B | APOL1 inhibitors and methods of use thereof | 弗特克斯药品有限公司 | 2024-05-24 | — | — | CN | disclosed |