SCHEMBL31006375

SCHEMBL31006375

O=C(CCc1c(-c2ccc(F)cc2)[nH]c2ccccc12)N[C@H]1C(=O)NC[C@@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ APOL1 O14791 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31006378 1.00 APOL1 (1.00) APOL1
SCHEMBL22118344 1.00 APOL1 (1.00) APOL1
SCHEMBL31006362 1.00 APOL1 (1.00) APOL1
SCHEMBL31006360 1.00 APOL1 (1.00) APOL1
SCHEMBL22160167 1.00 APOL1 (1.00) APOL1
SCHEMBL22118479 1.00 APOL1 (1.00) APOL1
SCHEMBL22118433 1.00 APOL1 (1.00) APOL1
SCHEMBL22118316 1.00 APOL1 (1.00) APOL1
SCHEMBL22160197 0.93 APOL1 (1.00) APOL1
SCHEMBL22161158 0.92 APOL1 (0.85) APOL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113453760-B APOL1 inhibitors and methods of use thereof 弗特克斯药品有限公司 2024-05-24 — — CN disclosed
Send feedback