SCHEMBL31006380

SCHEMBL31006380

C=Cc1cccc2c(CCC(=O)N[C@@H]3C(=O)NC[C@H]3O)c(-c3ccccc3)[nH]c12

nearest known ligand 0.77

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
APOL1 O14791 20/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31006381 1.00 APOL1 (0.77) APOL1
SCHEMBL22118374 1.00 APOL1 (0.77) APOL1
SCHEMBL22160351 0.87 APOL1 (0.80) APOL1
SCHEMBL22747586 0.87 APOL1 (1.00) APOL1
SCHEMBL22161136 0.86 APOL1 (0.79) APOL1
SCHEMBL30218287 0.86 APOL1 (0.76) APOL1
SCHEMBL22161268 0.86 APOL1 (0.76) APOL1
SCHEMBL22161107 0.86 APOL1 (0.76) APOL1
SCHEMBL22161137 0.86 APOL1 (0.78) APOL1
SCHEMBL22161251 0.85 APOL1 (0.83) APOL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113453760-B APOL1 inhibitors and methods of use thereof 弗特克斯药品有限公司 2024-05-24 CN disclosed