Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOL1 | O14791 | 20/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22161396 | 1.00 | APOL1 (0.69) | APOL1 | |
| SCHEMBL22160132 | 0.93 | APOL1 (0.79) | APOL1 | |
| SCHEMBL31006384 | 0.93 | APOL1 (0.79) | APOL1 | |
| SCHEMBL22161153 | 0.92 | APOL1 (0.71) | APOL1 | |
| SCHEMBL22160352 | 0.90 | APOL1 (0.73) | APOL1 | |
| SCHEMBL22160056 | 0.88 | APOL1 (0.88) | APOL1 | |
| SCHEMBL22159649 | 0.87 | APOL1 (0.72) | APOL1 | |
| SCHEMBL22160351 | 0.87 | APOL1 (0.80) | APOL1 | |
| SCHEMBL22161346 | 0.86 | APOL1 (0.75) | APOL1 | |
| SCHEMBL22161061 | 0.85 | APOL1 (0.83) | APOL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113453760-B | APOL1 inhibitors and methods of use thereof | 弗特克斯药品有限公司 | 2024-05-24 | — | — | CN | disclosed |