Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 19/20 | 0.66 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.64 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.58 |
| ▸ | GSK3B | P49841 | 1/20 | 0.58 |
| ▸ | CDK9 | P50750 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29283821 | 1.00 | DYRK1A (0.66) | DYRK1ADYRK1BCCNT1GSK3BCDK9 | |
| SCHEMBL12281648 | 0.83 | DYRK1B (0.73) | DYRK1ADYRK1BGSK3BCDK9 | |
| SCHEMBL30233270 | 0.83 | DYRK1B (0.73) | DYRK1ADYRK1BGSK3BCDK9 | |
| SCHEMBL26174562 | 0.81 | DYRK1A (0.67) | DYRK1ADYRK1BCCNT1GSK3BCDK9 | |
| SCHEMBL29283838 | 0.80 | DYRK1A (0.58) | DYRK1ADYRK1BGSK3B | |
| SCHEMBL31006597 | 0.80 | DYRK1A (1.00) | DYRK1ACCNT1GSK3BCDK9 | |
| SCHEMBL29283910 | 0.80 | DYRK1A (1.00) | DYRK1ACCNT1GSK3BCDK9 | |
| SCHEMBL21318714 | 0.79 | MAP4K4 (0.67) | — | |
| SCHEMBL26174558 | 0.78 | DYRK1B (0.69) | DYRK1ADYRK1BGSK3BCDK9 | |
| SCHEMBL20292829 | 0.78 | DYRK1B (1.00) | DYRK1ADYRK1BCCNT1GSK3BCDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184650-A | 6- (1H-pyrrolo [2,3-b ] pyridin-3-yl) quinazoline-4-amine derivative, and preparation method and application thereof | 中国人民解放军北部战区总医院 | 2024-06-14 | — | — | CN | claimed |
| CN-118184650-A | 6- (1H-pyrrolo [2,3-b ] pyridin-3-yl) quinazoline-4-amine derivative, and preparation method and application thereof | 中国人民解放军北部战区总医院 | 2024-06-14 | — | — | CN | disclosed |
| CN-118184650-A | 6- (1H-pyrrolo [2,3-b ] pyridin-3-yl) quinazoline-4-amine derivative, and preparation method and application thereof | 中国人民解放军北部战区总医院 | 2024-06-14 | — | — | CN | disclosed |
| CN-118184650-A | 6- (1H-pyrrolo [2,3-b ] pyridin-3-yl) quinazoline-4-amine derivative, and preparation method and application thereof | 中国人民解放军北部战区总医院 | 2024-06-14 | — | — | CN | disclosed |