Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 20/20 | 1.00 |
| ▸ | CDK9 | P50750 | 20/20 | 1.00 |
| ▸ | CCNK | O75909 | 18/20 | 1.00 |
| ▸ | CDK12 | Q9NYV4 | 18/20 | 1.00 |
| ▸ | CCNE1 | P24864 | 17/20 | 1.00 |
| ▸ | CDK2 | P24941 | 17/20 | 1.00 |
| ▸ | CDK7 | P50613 | 10/20 | 0.77 |
| ▸ | CCNH | P51946 | 9/20 | 0.77 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.77 |
| ▸ | MNAT1 | P51948 | 8/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24839793 | 1.00 | CCNT1 (1.00) | CCNT1CDK9CCNKCDK12CCNE1 | |
| Hydrochloric Acid SCHEMBL31006880 | 0.99 | CCNT1 (0.98) | CCNT1CDK9CCNKCDK12CCNE1 | |
| SCHEMBL25328954 | 0.94 | CCNK (0.89) | CCNT1CDK9CCNKCDK12CCNE1 | |
| SCHEMBL25328959 | 0.94 | CCNK (0.89) | CCNT1CDK9CCNKCDK12CCNE1 | |
| Hydrochloric Acid SCHEMBL31006785 | 0.93 | CCNK (0.87) | CCNT1CDK9CCNKCDK12CCNE1 | |
| SCHEMBL24839342 | 0.87 | CCNT1 (1.00) | CCNT1CDK9CCNKCDK12CCNE1 | |
| SCHEMBL20190945 | 0.87 | CCNT1 (1.00) | CCNT1CDK9CCNKCDK12CCNE1 | |
| SCHEMBL29613489 | 0.87 | CCNT1 (1.00) | CCNT1CDK9CCNKCDK12CCNE1 | |
| SCHEMBL20190942 | 0.87 | CCNT1 (1.00) | CCNT1CDK9CCNKCDK12CCNE1 | |
| SCHEMBL29749340 | 0.86 | CCNT1 (0.78) | CCNT1CDK9CCNKCDK12CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118480029-A | 2-Aminopyrimidine compound or salt thereof, and preparation method and application thereof | 励缔(杭州)医药科技有限公司 | 2024-08-13 | — | — | CN | disclosed |