SCHEMBL3100703

SCHEMBL3100703

NCc1nn(-c2ccc(Cl)cc2Cl)c(-c2ccc(Br)[se]2)c1Br

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
OPRL1 P41146 7/20 0.39
KCNH2 Q12809 3/20 0.39
CNR2 P34972 5/20 0.36
CNR1 P21554 5/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3103712 0.88 OPRL1 (0.39) OPRL1KCNH2CNR2CNR1
SCHEMBL3103491 0.81 OPRL1 (0.36) OPRL1KCNH2CNR2CNR1
SCHEMBL3100716 0.79 CNR2 (0.39) OPRL1KCNH2CNR2CNR1
SCHEMBL3094639 0.79 CNR2 (0.47) CNR2CNR1
SCHEMBL3096422 0.78 CNR2 (0.48) CNR2CNR1
SCHEMBL3087634 0.77 CNR1 (0.47) OPRL1KCNH2CNR2CNR1
SCHEMBL3089140 0.76 CNR1 (0.49) OPRL1KCNH2CNR2CNR1
SCHEMBL3096383 0.76 KDM4E (0.52) CNR2CNR1
SCHEMBL3092984 0.75 ALOX12 (0.49) OPRL1KCNH2CNR2CNR1
SCHEMBL3096369 0.75 CNR1 (0.49) OPRL1KCNH2CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2012149-B1 RETARDATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY KONICA MINOLTA OPTO INC (JP) 2018-02-14 EP disclosed
US-9272448-B2 Cellulose resin film, process for producing cellulose resin film, antireflection film, polarizing plate, and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2016-03-01 US disclosed
US-9243131-B2 Retardation film, polarizing plate and liquid crystal display device KONICA MINOLTA OPTO, INC. (JP) 2016-01-26 US disclosed
US-7803293-B2 Optical film manufacturing method, optical film manufacturing apparatus and optical film KONICA MINOLTA OPTO, INC. (JP) 2010-09-28 US disclosed
US-7803799-B2 such as 1-(2,4-dichlorophenyl)-N-(piperidin-1-yl)-5-(selenophen-2-yl)-1H-pyrazole-3-carboxamide, used for treating cannabinoid-receptor mediated disorders selected from obesity, metabolic syndrome, drug abuse and dependence or neuropathic pain NATIONAL HEALTH RESEARCH INSTITUTES (TW) 2010-09-28 US disclosed
US-7495720-B2 Polarizing plate and liquid crystal display device KONICA MINOLTA OPTO, INC. (JP) 2009-02-24 US disclosed
EP-2012149-A1 RETARDATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY Konica Minolta Opto, Inc. (JP) 2009-01-07 EP disclosed
US-20080246189-A1 Cellulose Resin Film, Process for Producing Cellulose Resin Film, Antireflection Film, Polarizing Plate, and Liquid Crystal Display KONICA MINOLTA OPTO, INC. (JP) 2008-10-09 US disclosed
US-20080021031-A1 SELENOPHENE COMPOUNDS NATIONAL HEALTH RESEARCH INSTITUTE (TW) 2008-01-24 US disclosed
US-20070247576-A1 Retardation film, polarizing plate and liquid crystal display device KONICA MINOLTA OPTO, INC. (JP) 2007-10-25 US disclosed
US-20070085228-A1 OPTICAL FILM MANUFACTURING METHOD, OPTICAL FILM MANUFACTURING APPARATUS AND OPTICAL FILM KONICA MINOLTA OPTO, INC. (JP) 2007-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080021031-A1 SELENOPHENE COMPOUNDS CNR2, CNR1, SELENOI OPRL1 14/4885KCNH2 3042/4885CNR2 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.