Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 20/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13157915 | 1.00 | CCR1 (0.60) | CCR1CYP2C19KCNH2 | |
| SCHEMBL3096749 | 0.88 | CCR1 (0.58) | CCR1CYP2C19KCNH2 | |
| SCHEMBL13157918 | 0.88 | CCR1 (0.58) | CCR1CYP2C19KCNH2 | |
| SCHEMBL4824445 | 0.84 | CCR1 (0.64) | CCR1CYP2C19KCNH2 | |
| SCHEMBL14566241 | 0.78 | CCR1 (0.64) | CCR1CYP2C19KCNH2 | |
| SCHEMBL14016489 | 0.78 | CCR1 (0.54) | CCR1CYP2C19KCNH2 | |
| SCHEMBL2876592 | 0.76 | CCR1 (1.00) | CCR1CYP2C19KCNH2 | |
| SCHEMBL3105142 | 0.76 | POLB (0.55) | — | |
| SCHEMBL13158203 | 0.76 | POLB (0.55) | — | |
| SCHEMBL13157795 | 0.76 | POLB (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399455-B2 | Compounds useful as chemokine receptor antagonists | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2013-03-19 | — | — | US | disclosed |
| US-20100234356-A1 | COMPOUNDS USEFUL AS CHEMOKINE RECEPTOR ANTAGONISTS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2010-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234356-A1 | COMPOUNDS USEFUL AS CHEMOKINE RECEPTOR ANTAGONISTS | ACKR3, CCR5, CXCR2 | CCR1 11/4885CYP2C19 2973/4885KCNH2 4153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.