SCHEMBL3100797

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8187226	0.83	HRH3 (0.61)	HRH3GPR84MAOBDRD2DRD1
	SCHEMBL3094817	0.80	HRH3 (0.67)	HRH3MAOBHRH1CYP2D6
	SCHEMBL3098179	0.80	MAOB (0.50)	HRH3MAOBHRH1CYP2D6
	SCHEMBL3101138	0.80	MAOB (0.53)	HRH3GPR84MAOBHRH1FFAR1
	SCHEMBL3100790	0.78	HRH3 (0.67)	HRH3GPR84HRH1CYP2D6
	SCHEMBL3091201	0.77	HRH3 (0.47)	HRH3HRH1CYP2D6KDM4EALDH1A1
	SCHEMBL3082474	0.76	MAOB (0.42)	HRH3MAOBHRH1CYP2D6DRD2
	SCHEMBL14563191	0.75	HRH3 (0.44)	HRH3HRH1CYP2D6
	SCHEMBL1792134	0.74	DRD2 (0.46)	CYP2D6DRD2KDM4EALDH1A1DRD1
	SCHEMBL3101101	0.74	HRH3 (0.51)	HRH3HRH1CYP2D6ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.