Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.30 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.30 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30226481 | 1.00 | HSD11B1 (0.33) | HSD11B1APEX1BLMCHRM2CHRM4 | |
| SCHEMBL31009117 | 1.00 | HSD11B1 (0.33) | HSD11B1APEX1BLMCHRM2CHRM4 | |
| SCHEMBL14885224 | 0.85 | APEX1 (0.33) | APEX1BLM | |
| SCHEMBL14885178 | 0.85 | APEX1 (0.33) | APEX1BLM | |
| SCHEMBL25131301 | 0.83 | CHRM2 (0.35) | HSD11B1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL19992910 | 0.83 | HSD11B1 (0.33) | HSD11B1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL30965278 | 0.81 | APEX1 (0.33) | APEX1BLMRAB9A | |
| SCHEMBL25646827 | 0.76 | HSD11B1 (0.34) | HSD11B1 | |
| SCHEMBL19143872 | 0.74 | — | — | |
| SCHEMBL25646822 | 0.74 | HSD11B1 (0.33) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201915-A | Pyridazinylamino derivatives as ALK5 inhibitors | 奇斯药制品公司 | 2024-06-14 | — | — | CN | claimed |
| CN-118201915-A | Pyridazinylamino derivatives as ALK5 inhibitors | 奇斯药制品公司 | 2024-06-14 | — | — | CN | disclosed |