Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29218594 | 1.00 | SLC6A3 (0.45) | SLC6A3SLC6A4SLC6A2KDM1AOPRL1 | |
| SCHEMBL25155197 | 0.85 | SLC6A3 (0.53) | SLC6A3SLC6A4SLC6A2KDM4EMEN1 | |
| SCHEMBL29876796 | 0.85 | SLC6A3 (0.53) | SLC6A3SLC6A4SLC6A2KDM4EMEN1 | |
| SCHEMBL25155130 | 0.82 | SLC6A3 (0.54) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL30343860 | 0.82 | SLC6A3 (0.54) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL20104711 | 0.80 | SLC6A3 (0.62) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL4510593 | 0.74 | AHR (0.39) | MAPK1 | |
| SCHEMBL25155278 | 0.73 | SLC6A3 (0.45) | SLC6A3SLC6A4SLC6A2KDM1AKDM4E | |
| SCHEMBL30344926 | 0.73 | SLC6A3 (0.45) | SLC6A3SLC6A4SLC6A2KDM1AKDM4E | |
| SCHEMBL4510596 | 0.72 | SLC6A4 (0.45) | SLC6A3SLC6A4SLC6A2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118076581-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-24 | — | — | CN | disclosed |