Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 8/20 | 0.33 |
| ▸ | PPARD | Q03181 | 8/20 | 0.33 |
| ▸ | PPARA | Q07869 | 8/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30847718 | 0.82 | POLQ (0.39) | POLQ | |
| SCHEMBL31009144 | 0.77 | POLQ (0.39) | POLQ | |
| SCHEMBL31009194 | 0.77 | POLQ (0.44) | POLQ | |
| SCHEMBL30847687 | 0.76 | POLQ (0.37) | POLQ | |
| SCHEMBL29317081 | 0.76 | PPARD (0.35) | PPARGPPARDPPARA | |
| SCHEMBL29313701 | 0.75 | POLQ (0.37) | POLQ | |
| SCHEMBL31009165 | 0.74 | POLQ (0.46) | POLQ | |
| SCHEMBL30847634 | 0.73 | POLQ (0.48) | POLQ | |
| SCHEMBL30847773 | 0.72 | POLQ (0.48) | POLQ | |
| SCHEMBL31009150 | 0.72 | POLQ (0.41) | POLQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024147972-A2 | DNA POLYMERASE THETA INHIBITORS CONTAINING NON-SATURATED 5-MEMBERED HETEROCYCLIC RINGS AND USE THEREOF | THOMAS JEFFERSON UNIVERSITY (US) | 2024-07-11 | — | — | WO | disclosed |