Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 6/20 | 0.48 |
| ▸ | TACR1 | P25103 | 2/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
| ▸ | CETP | P11597 | 1/20 | 0.30 |
| ▸ | LIPE | Q05469 | 2/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30847765 | 0.89 | POLQ (0.46) | POLQTACR1LIPG | |
| SCHEMBL30847634 | 0.87 | POLQ (0.48) | POLQTLR7LIPE | |
| SCHEMBL30847618 | 0.81 | POLQ (0.43) | POLQTACR1 | |
| SCHEMBL31009165 | 0.81 | POLQ (0.46) | POLQ | |
| SCHEMBL31009194 | 0.81 | POLQ (0.44) | POLQ | |
| SCHEMBL30847678 | 0.79 | POLQ (0.43) | POLQ | |
| SCHEMBL31009150 | 0.77 | POLQ (0.41) | POLQTACR1 | |
| SCHEMBL30847728 | 0.76 | POLQ (0.42) | POLQTACR1LIPE | |
| SCHEMBL30847621 | 0.76 | POLQ (0.61) | POLQLIPE | |
| SCHEMBL29314384 | 0.75 | POLQ (0.52) | POLQTACR1TLR7LIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4598901-A1 | PYRROLIDINE AND IMIDAZOLIDINE BASED DNA POLYMERASE THETA INHIBITORS AND USE THEREOF | Thomas Jefferson University (US) | 2025-08-13 | — | — | EP | disclosed |
| WO-2024076964-A1 | PYRROLIDINE AND IMIDAZOLIDINE BASED DNA POLYMERASE THETA INHIBITORS AND USE THEREOF | THOMAS JEFFERSON UNIVERSITY (US) | 2024-04-11 | — | — | WO | disclosed |