SCHEMBL3101030

SCHEMBL3101030

C=CC[Si](Cl)(Cl)CCCCCC

nearest known ligand 0.44

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.44
ALDH1A1 P00352 2/20 0.37
FAAH O00519 1/20 0.36
THRB P10828 1/20 0.35
ZDHHC20 Q5W0Z9 1/20 0.34
ZDHHC2 Q9UIJ5 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2491733 0.98 TSHR (0.41) TSHRALDH1A1FAAHTHRBZDHHC20
SCHEMBL6063886 0.91 TSHR (0.40) TSHRALDH1A1FAAH
SCHEMBL28447500 0.83 TSHR (0.44) TSHRALDH1A1FAAHTHRBZDHHC20
SCHEMBL6062975 0.81
SCHEMBL31414062 0.81 TSHR (0.67) TSHRALDH1A1FAAH
SCHEMBL28483750 0.80 TSHR (0.41) TSHRALDH1A1
SCHEMBL20473659 0.80 TSHR (0.41) TSHRALDH1A1
SCHEMBL2763894 0.78 TSHR (0.50) TSHRALDH1A1THRB
SCHEMBL11313336 0.78 TSHR (0.50) TSHRALDH1A1THRB
SCHEMBL134147 0.78 TSHR (0.50) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116120360-A Silyl ether connected furyl dialdehyde compound and preparation method thereof 中国科学技术大学 2023-05-16 CN disclosed
CN-106137774-B Pit and fissure sealant based on tooth surface hydrophobization concept 浙江大学 2020-04-17 CN disclosed
CN-110191889-A Silsesquioxane derivative, its composition and low cure shrinkage cured film with free-radical polymerised functional group 捷恩智株式会社 2019-08-30 CN disclosed
CN-103665018-B Silane compound and preparation method thereof 中国石油化工股份有限公司 2017-02-15 CN disclosed
US-9170492-B2 Silicon-containing film-forming composition, silicon-containing film, and pattern forming method JSR CORPORATION (JP) 2015-10-27 US disclosed
US-9140985-B2 2015-09-22 US disclosed
US-8299185-B2 Curable cage-type silicone copolymer and process for production thereof and curable resin composition comprising curable cage-type silicone copolymer and cured product thereof NIPPON STEEL CHEMICAL CO., LTD. (JP) 2012-10-30 US disclosed
US-20100280190-A1 CURABLE CAGE-TYPE SILICONE COPOLYMER AND PROCESS FOR PRODUCTION THEREOF AND CURABLE RESIN COMPOSITION COMPRISING CURABLE CAGE-TYPE SILICONE COPOLYMER AND CURED PRODUCT THEREOF NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2010-11-04 US disclosed
US-20100233632-A1 SILICON-CONTAINING FILM-FORMING COMPOSITION, SILICON-CONTAINING FILM, AND PATTERN FORMING METHOD JSR CORPORATION (JP) 2010-09-16 US disclosed
EP-1428795-B1 SILSESQUIOXANE DERIVATIVES AND PROCESS FOR PRODUCTION THEREOF CHISSO CORP (JP) 2009-07-22 EP disclosed
EP-1428795-A1 SILSESQUIOXANE DERIVATIVES AND PROCESS FOR PRODUCTION THEREOF CHISSO CORPORATION (JP) 2004-06-16 EP disclosed
US-20040097366-A1 Polyolefin-based composite resin, method for production thereof, catalyst for polymerization of vinly compound and method for polymerization of vinly compound using the same IDEMITSU KOSAN CO. LTD. (JP) 2004-05-20 US disclosed
US-20030072932-A1 Transparent substrate coated with a polymer layer SAINT-GOBAIN GLASS FRANCE (FR) 2003-04-17 US disclosed
US-20030045648-A1 (Meth)acryloyl group-modified ethylene-alpha-olefin copolymer, production method thereof and rubber composition JSR CORPORATION (JP) 2003-03-06 US disclosed
EP-1266912-A1 (Meth)acryloyl group-modified ethylene-alpha-olefin copolymer, production method thereof and rubber composition JSR Corporation (JP) 2002-12-18 EP disclosed
US-5780661-A Process for preparing allylsilane compound derivatives DOW CORNING ASIA, LTD. (JP) 1998-07-14 US disclosed
US-5760263-A Alkylferrocenes containing chlorosilyl groups and their preparation methods KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 1998-06-02 US disclosed
EP-0812848-A2 Process for preparing allylsilane compound derivatives DOW CORNING ASIA, Ltd. (JP) 1997-12-17 EP disclosed
US-5523444-A REACTING (SUBSTITUTED)AROMATIC COMPOUNDS WITH ALLYLCHLOROSILANES IN PRESENCE OF LEWIS ACID CATALYSTS KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 1996-06-04 US disclosed
US-5420323-A Hydrosilation KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 1995-05-30 US disclosed