SCHEMBL2491733

SCHEMBL2491733

C=CC[Si](Cl)(Cl)CCCCC

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.41
ALDH1A1 P00352 1/20 0.39
FAAH O00519 1/20 0.33
ZDHHC20 Q5W0Z9 1/20 0.31
ZDHHC2 Q9UIJ5 1/20 0.31
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3101030 0.98 TSHR (0.44) TSHRALDH1A1FAAHZDHHC20ZDHHC2
SCHEMBL6063886 0.93 TSHR (0.40) TSHRALDH1A1FAAH
SCHEMBL6062975 0.83
SCHEMBL28447500 0.80 TSHR (0.44) TSHRALDH1A1FAAHZDHHC20ZDHHC2
SCHEMBL20473670 0.79 TSHR (0.37) TSHRALDH1A1
SCHEMBL31414062 0.78 TSHR (0.67) TSHRALDH1A1FAAH
SCHEMBL9224739 0.78 ALDH1A1 (0.33) TSHRALDH1A1
SCHEMBL28483750 0.77 TSHR (0.41) TSHRALDH1A1
SCHEMBL20473659 0.77 TSHR (0.41) TSHRALDH1A1
SCHEMBL133247 0.77 TSHR (0.44) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8013052-B2 Curable resin, production method thereof, epoxy resin composition, and electronic device HITACHI CHEMICAL COMPANY, LTD. (JP) 2011-09-06 US disclosed
US-20090023855-A1 NOVEL CURABLE RESIN, PRODUCTION METHOD THEREOF, EPOXY RESIN COMPOSITION, AND ELECTRONIC DEVICE RESONAC CORPORATION (JP) 2009-01-22 US disclosed
EP-0017122-B1 USE OF VONEL QUATERNARY POLYSILOXANE DERIVATIVES IN HAIR COSMETICS, AND HAIR WASHING AND HAIR TREATMENT COMPOSITIONS CONTAINING THEM Henkel Kommanditgesellschaft auf Aktien (DE) 1983-06-15 EP disclosed
EP-0017122-A1 Use of vonel quaternary polysiloxane derivatives in hair cosmetics, and hair washing and hair treatment compositions containing them Henkel Kommanditgesellschaft auf Aktien (DE) 1980-10-15 EP disclosed