Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.35 |
| ▸ | CSF1R | P07333 | 2/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25317161 | 1.00 | ESR1 (0.43) | ESR1ESR2BACE1PDGFRBPDGFRA | |
| SCHEMBL25317059 | 0.87 | PDGFRB (0.47) | ESR1ESR2BACE1PDGFRBPDGFRA | |
| SCHEMBL25317420 | 0.87 | ESR1 (0.40) | ESR1ESR2BACE1PDGFRBPDGFRA | |
| SCHEMBL25914664 | 0.85 | ESR1 (0.38) | ESR1ESR2BACE1PDGFRBPDGFRA | |
| SCHEMBL25913396 | 0.84 | ESR2 (0.46) | ESR1ESR2BACE1PDGFRBPDGFRA | |
| SCHEMBL25913145 | 0.84 | ESR1 (0.37) | ESR1ESR2BACE1PDGFRBPDGFRA | |
| SCHEMBL25914415 | 0.83 | PDGFRB (0.35) | PDGFRBPDGFRACSF1RLCKKIT | |
| SCHEMBL25316199 | 0.83 | ESR2 (0.44) | ESR1ESR2BACE1PDGFRBPDGFRA | |
| SCHEMBL25322198 | 0.81 | ESR2 (0.43) | ESR1ESR2BACE1PDGFRBPDGFRA | |
| SCHEMBL25913124 | 0.81 | ESR1 (0.43) | ESR1ESR2BACE1PDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118434727-A | Substituted pyrimidinone derivatives, pharmaceutical compositions and pharmaceutical uses thereof | 上海海雁医药科技有限公司 | 2024-08-02 | — | — | CN | disclosed |