Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 4/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.35 |
| ▸ | CSF1R | P07333 | 2/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.32 |
| ▸ | SRC | P12931 | 4/20 | 0.32 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | ABL1 | P00519 | 2/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
| ▸ | WEE1 | P30291 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25317492 | 0.87 | PDGFRB (0.35) | PDGFRBPDGFRACSF1RLCKKIT | |
| SCHEMBL25914850 | 0.87 | EGFR (0.35) | PDGFRBPDGFRACSF1RLCKKIT | |
| SCHEMBL25319475 | 0.87 | CSF1R (0.47) | PDGFRBPDGFRACSF1RLCKKIT | |
| SCHEMBL25914414 | 0.84 | CSF1R (0.37) | PDGFRBPDGFRACSF1RLCKKIT | |
| SCHEMBL25317161 | 0.83 | ESR1 (0.43) | PDGFRBPDGFRACSF1RLCKKIT | |
| SCHEMBL31010902 | 0.83 | ESR1 (0.43) | PDGFRBPDGFRACSF1RLCKKIT | |
| SCHEMBL25914470 | 0.76 | CSF1R (0.42) | PDGFRBPDGFRACSF1RLCKKIT | |
| SCHEMBL25910804 | 0.75 | BRAF (0.44) | PDGFRBPDGFRACSF1RLCKKIT | |
| SCHEMBL25914418 | 0.75 | CSF1R (0.41) | PDGFRBPDGFRACSF1RLCKKIT | |
| SCHEMBL25910935 | 0.74 | PDGFRB (0.39) | PDGFRBPDGFRACSF1RLCKKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125812-A1 | SUBSTITUTED PYRIMIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |