Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 2/20 | 0.46 |
| ▸ | JAK1 | P23458 | 2/20 | 0.46 |
| ▸ | TYK2 | P29597 | 2/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15649981 | 1.00 | KMT2A (0.53) | KMT2AMEN1MAPK10GFERRAB9A | |
| SCHEMBL20385536 | 0.85 | MKNK1 (0.51) | KMT2AMEN1RAB9ANPC1JAK2 | |
| Hydrochloric Acid SCHEMBL4901670 | 0.83 | TP53 (0.47) | KMT2AMEN1MAPK10GFERRAB9A | |
| SCHEMBL26910995 | 0.81 | KMT2A (0.64) | KMT2AMEN1MAPK10GFERRAB9A | |
| SCHEMBL221242 | 0.81 | KMT2A (0.76) | KMT2AMEN1MAPK10GFERRAB9A | |
| SCHEMBL29391624 | 0.81 | KMT2A (0.76) | KMT2AMEN1MAPK10GFERRAB9A | |
| SCHEMBL30541040 | 0.81 | MEN1 (0.53) | KMT2AMEN1MAPK10GFERRAB9A | |
| SCHEMBL3266384 | 0.80 | MEN1 (0.52) | KMT2AMEN1MAPK10GFERJAK2 | |
| SCHEMBL16245640 | 0.79 | ALDH1A1 (0.51) | KMT2AMEN1MAPK10MAPK1JAK2 | |
| SCHEMBL6574416 | 0.79 | KMT2A (0.73) | KMT2AMEN1MAPK10GFERRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114787142-B | Compounds as cyclin dependent kinase 9 inhibitors and uses thereof | 石药集团中奇制药技术（石家庄）有限公司 | 2024-08-02 | — | — | CN | disclosed |