⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14506018 | 1.00 | — | — | |
| Biphenyl SCHEMBL27408392 | 0.84 | ALDH1A1 (0.39) | — | |
| SCHEMBL27789557 | 0.82 | — | — | |
| SCHEMBL6649079 | 0.78 | — | — | |
| SCHEMBL14506020 | 0.78 | — | — | |
| SCHEMBL20524429 | 0.78 | — | — | |
| SCHEMBL8164385 | 0.76 | — | — | |
| SCHEMBL3655648 | 0.76 | — | — | |
| SCHEMBL337118 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL28119660 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102603724-B | Method for purifying and refining dimethoxy taxane compound | JIANGSU HONGDOUSHAN BIOLOG TECHNOLOGY CO LTD | 2014-02-26 | — | — | CN | claimed |
| US-RE40120-E1 | Process for the preparation of taxanes from 10-deacetylbaccatin III | INDENA S.P.A. (IT) | 2008-02-26 | — | — | US | claimed |
| US-6900342-B2 | Anticancer taxanes such as paclitaxel, docetaxel and their structural analogs, and a method for the preparation thereof | DABUR INDIA LIMITED (IN) | 2005-05-31 | — | — | US | claimed |
| US-20040073044-A1 | Anticancer taxanes such as paclitaxel, docetaxel and their structural analogs, and a method for the preparation thereof | DABUR PHARMA LIMITED (IN) | 2004-04-15 | — | — | US | claimed |
| US-6500966-B1 | PROTECTING THE 7- AND 10- HYDROXYLS AND ESTERIFYING THE C-13 HYDROXYL WITH AN OXAZOLIDINE 5-CARBOXYLIC ACID; DEPROTECTING AND OPTIONALLY ACETYLATING THE C-10 HYDROXYL GROUP; DECYCLI-ZATION OF THE OXAZOLIDINE RING | INDENA S.P.A. (IT) | 2002-12-31 | — | — | US | claimed |
| CN-1259012-A | Fungicidal mixtures | BASF AG (DE) | 2000-07-05 | — | — | CN | claimed |
| CN-1204329-A | (2R,3S) -3-tert-butoxycarbonylamino-2-hydroxy-3-phenylpropionic acid taxol-11-en-13 alpha-ester dihydrate and preparation method thereof | RHONE POULENC RORER SA (FR) | 1999-01-06 | — | — | CN | claimed |
| EP-0669915-B1 | METHOD FOR THE PREPARATION OF A 1,3-OXAZOLIDINE-5-CARBOXYLIC ACID | RHONE POULENC RORER SA (FR) | 1997-06-18 | — | — | EP | claimed |
| CN-106458939-B | * oxazolidinyl compound and the selective androgen receptor agonist comprising the compound | 东亚ST株式会社 | 2019-05-17 | — | — | CN | disclosed |
| CN-107848990-A | The manufacture method of the side chain precursor of taxol and Docetaxel | 万代忠胜 | 2018-03-27 | — | — | CN | disclosed |
| CN-104803916-B | Hete rocyclic derivatives as SARM (SARMS) | 詹森药业有限公司 | 2017-08-11 | — | — | CN | disclosed |
| CN-106905386-A | Aminoglycoside derivative | 莱姆派克斯制药公司 | 2017-06-30 | — | — | CN | disclosed |
| CN-106458939-A | Oxazolidine-based compound and selective androgen receptor agonist comprising same | 东亚ST株式会社 | 2017-02-22 | — | — | CN | disclosed |
| WO-2015087228-A1 | PROCESS FOR THE PREPARATION OF CABAZITAXEL AND ITS SOLVATES | Mylan Laboratories Ltd. (IN) | 2015-06-18 | — | — | WO | disclosed |
| CN-1129217-A | Baccatin derivatives and processes for the preparing the same | TANABE SEIYAKU CO (JP) | 1996-08-21 | — | — | CN | disclosed |
| CN-1031824-C | Thiazolidinone and oxazolidinone derivatives | SANKYO CO (JP) | 1996-05-22 | — | — | CN | disclosed |
| CN-1113435-A | Preparation of pharmaceutical composition containing novel thiazolidone and oxazolidone | SANKYO CO (JP) | 1995-12-20 | — | — | CN | disclosed |
| EP-0669915-A1 | METHOD FOR THE PREPARATION OF 1,3-OXAZOLIDIN 5-CARBOXYLIC ACID. | RHONE POULENC RORER SA (FR) | 1995-09-06 | — | — | EP | disclosed |
| WO-1994012482-A1 | METHOD FOR THE PREPARATION OF 1,3-OXAZOLIDIN 5-CARBOXYLIC ACID | RHONE-POULENC RORER S.A. (FR) | 1994-06-09 | — | — | WO | disclosed |
| CN-1066067-A | THIAZOLIDINONE AND OXAZOLIDINONE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS VASODILATORS | SANKYO CO (JP) | 1992-11-11 | — | — | CN | disclosed |