Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 17/20 | 0.84 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.81 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21632457 | 0.99 | NLRP3 (0.85) | NLRP3KCNH2SLC18A2TP53 | |
| SCHEMBL21677411 | 0.92 | NLRP3 (0.82) | NLRP3KCNH2SLC18A2TP53 | |
| SCHEMBL21632361 | 0.91 | NLRP3 (1.00) | NLRP3KCNH2SLC18A2TP53 | |
| SCHEMBL21632149 | 0.91 | NLRP3 (0.75) | NLRP3KCNH2SLC18A2TP53 | |
| SCHEMBL21632315 | 0.91 | NLRP3 (0.75) | NLRP3KCNH2SLC18A2TP53 | |
| SCHEMBL21632325 | 0.91 | NLRP3 (0.75) | NLRP3KCNH2SLC18A2TP53 | |
| SCHEMBL23881929 | 0.90 | NLRP3 (0.80) | NLRP3KCNH2SLC18A2TP53 | |
| SCHEMBL21632181 | 0.90 | NLRP3 (0.80) | NLRP3KCNH2SLC18A2TP53 | |
| SCHEMBL21632138 | 0.90 | NLRP3 (0.80) | NLRP3KCNH2SLC18A2TP53 | |
| SCHEMBL21632127 | 0.90 | NLRP3 (1.00) | NLRP3KCNH2SLC18A2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3827008-B1 | NLRP3 INFLAMMASOME INHIBITORS | NOVARTIS AG (CH) | 2024-07-31 | — | — | EP | claimed |