Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | TYMP | P19971 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27378739 | 0.98 | TYR (0.37) | TYRLIPGKCNH2ALOX5MAPT | |
| SCHEMBL3645470 | 0.92 | HRH3 (0.34) | TYRHTTHCAR2TYMP | |
| SCHEMBL21310404 | 0.84 | — | — | |
| SCHEMBL28300226 | 0.81 | LIPG (0.38) | TYRLIPGKCNH2ALOX5MAPT | |
| SCHEMBL27671187 | 0.81 | LIPG (0.38) | TYRLIPGKCNH2ALOX5MAPT | |
| SCHEMBL28300224 | 0.81 | LIPG (0.38) | TYRLIPGKCNH2ALOX5MAPT | |
| Bromide SCHEMBL28162693 | 0.79 | LIPG (0.37) | TYRLIPGKCNH2ALOX5MAPT | |
| Bromide SCHEMBL28162683 | 0.79 | LIPG (0.37) | TYRLIPGKCNH2ALOX5MAPT | |
| Bromide SCHEMBL28162087 | 0.79 | LIPG (0.37) | TYRLIPGKCNH2ALOX5MAPT | |
| SCHEMBL370841 | 0.78 | TDP1 (0.35) | TYRLIPGKCNH2ALOX5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119490500-A | PRMT5 inhibitor, preparation method and application thereof | 上海艾力斯医药科技股份有限公司 | 2025-02-21 | — | — | CN | disclosed |
| CN-112203653-B | Compounds for the treatment of huntington's disease | PTC医疗公司 | 2024-08-16 | — | — | CN | disclosed |