Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.67 |
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.64 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.64 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.64 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.64 |
| ▸ | CSF1R | P07333 | 1/20 | 0.64 |
| ▸ | FER | P16591 | 1/20 | 0.64 |
| ▸ | CDK2 | P24941 | 1/20 | 0.64 |
| ▸ | MARK3 | P27448 | 1/20 | 0.64 |
| ▸ | FLT4 | P35916 | 1/20 | 0.64 |
| ▸ | FLT3 | P36888 | 1/20 | 0.64 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.64 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.64 |
| ▸ | CLK2 | P49760 | 1/20 | 0.64 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.64 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.64 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.64 |
| ▸ | STK3 | Q13188 | 1/20 | 0.64 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31014287 | 0.83 | NPSR1 (0.71) | NPSR1ATMKDM4EPRMT5WDR77 | |
| SCHEMBL1791310 | 0.81 | ATM (0.73) | NPSR1ATMKDM4EPKMALDH1A1 | |
| SCHEMBL31014290 | 0.81 | ATM (0.73) | NPSR1ATMKDM4EPKMALDH1A1 | |
| SCHEMBL1789828 | 0.81 | GSK3A (0.52) | CDK2DYRK1AKDM4EPRMT5WDR77 | |
| SCHEMBL29870198 | 0.81 | NPSR1 (1.00) | NPSR1ATMKDM4EALDH1A1GAA | |
| SCHEMBL581143 | 0.81 | NPSR1 (1.00) | NPSR1ATMKDM4EALDH1A1GAA | |
| SCHEMBL1785622 | 0.81 | NPSR1 (0.67) | NPSR1ATMKDM4EPRMT5ALDH1A1 | |
| SCHEMBL31014284 | 0.81 | NPSR1 (0.67) | NPSR1ATMKDM4EPRMT5ALDH1A1 | |
| SCHEMBL31014277 | 0.81 | NPSR1 (0.67) | NPSR1ATMCSF1RKDM4EPRMT5 | |
| SCHEMBL1362524 | 0.78 | CDK2 (0.75) | DCLK1PRKD3MAP4K4CHEK2CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118496166-A | Preparation method of phthalazinone compound | 五邑大学 | 2024-08-16 | — | — | CN | claimed |
| CN-118496166-A | Preparation method of phthalazinone compound | 五邑大学 | 2024-08-16 | — | — | CN | disclosed |