Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.45 |
| ▸ | EIF4E | P06730 | 3/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 4/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31015721 | 0.90 | EIF4E (0.49) | ADORA2AEIF4ECASP1HCRTR1HCRTR2 | |
| SCHEMBL31015632 | 0.86 | ADORA2A (0.45) | ADORA2AEIF4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL31015744 | 0.80 | ALDH1A1 (0.41) | ADORA2AEIF4EPPARGSCN2ASCN10A | |
| SCHEMBL24820105 | 0.80 | EIF4E (0.50) | EIF4ECASP1PPARGKDM4C | |
| SCHEMBL30792116 | 0.80 | EIF4E (0.50) | EIF4ECASP1PPARGKDM4C | |
| SCHEMBL31319278 | 0.78 | ADORA2A (0.46) | ADORA2AEIF4EPPARGCYP11B2GRM5 | |
| SCHEMBL24820114 | 0.78 | KDM4E (0.43) | EIF4ECASP1PPARGCYP11B2MEN1 | |
| SCHEMBL31319331 | 0.72 | ADORA2A (0.48) | ADORA2AHCRTR1HCRTR2PPARGCYP11B2 | |
| SCHEMBL31319310 | 0.72 | EIF4E (0.43) | EIF4ECASP1HCRTR1HCRTR2CYP11B2 | |
| SCHEMBL24820115 | 0.72 | ALDH1A1 (0.44) | EIF4EPPARGMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024153246-A1 | SUBSTITUTED TRICYCLIC COMPOUND AND USE THEREOF | 海南先声再明医药股份有限公司 | 2024-07-25 | — | — | WO | disclosed |