Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 5/20 | 0.33 |
| ▸ | PARP1 | P09874 | 8/20 | 0.33 |
| ▸ | TNKS | O95271 | 3/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31248148 | 0.80 | BCHE (0.40) | BCHE | |
| SCHEMBL31108716 | 0.80 | BCHE (0.40) | BCHE | |
| SCHEMBL22550209 | 0.70 | BRD4 (0.46) | BCHEBRD4RORC | |
| SCHEMBL29774541 | 0.70 | BRD4 (0.46) | BCHEBRD4RORC | |
| SCHEMBL19717275 | 0.67 | CTRB1 (0.40) | IDO1TDO2IDO2BCHEGABRA1 | |
| SCHEMBL29658759 | 0.67 | CTRB1 (0.40) | IDO1TDO2IDO2BCHEGABRA1 | |
| SCHEMBL24317752 | 0.65 | CYP1B1 (0.48) | BCHEGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL12576098 | 0.65 | PIK3CA (0.42) | IDO1TDO2IDO2BCHEGABRA1 | |
| SCHEMBL2954707 | 0.65 | PIK3CA (0.40) | BCHECYP4F2CYP4A11GABRA1GABRG2 | |
| SCHEMBL31108719 | 0.64 | BCHE (0.41) | BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024153246-A1 | SUBSTITUTED TRICYCLIC COMPOUND AND USE THEREOF | 海南先声再明医药股份有限公司 | 2024-07-25 | — | — | WO | disclosed |