Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.51 |
| ▸ | BCKDK | O14874 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | PRNP | P04156 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25212927 | 1.00 | RXFP1 (0.51) | RXFP1MCL1BCKDKNPC1RAB9A | |
| SCHEMBL25575157 | 0.85 | MCL1 (0.48) | RXFP1MCL1BCKDKNPC1RAB9A | |
| SCHEMBL2578736 | 0.84 | RXFP1 (0.53) | RXFP1MCL1BCKDKNPC1RAB9A | |
| SCHEMBL15619136 | 0.84 | MCL1 (0.53) | RXFP1MCL1BCKDKNPC1RAB9A | |
| SCHEMBL31015908 | 0.82 | BCKDK (0.49) | MCL1BCKDKNPC1RAB9AMAPT | |
| SCHEMBL31015931 | 0.82 | KDM4E (0.64) | RXFP1MCL1BCKDKNPC1RAB9A | |
| SCHEMBL31015986 | 0.82 | RXFP1 (0.51) | RXFP1MCL1BCKDKNPC1RAB9A | |
| SCHEMBL25257143 | 0.82 | RXFP1 (0.51) | RXFP1MCL1BCKDKNPC1RAB9A | |
| SCHEMBL25211925 | 0.82 | BCKDK (0.49) | MCL1BCKDKNPC1RAB9AMAPT | |
| SCHEMBL8142110 | 0.82 | KDM4E (0.64) | RXFP1MCL1BCKDKNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118451066-A | 3-Phenyl-1-benzothiophene-2-carboxylic acid derivatives as inhibitors of branched alpha ketoacid dehydrogenase kinase for the treatment of diabetes, kidney disease, NASH and heart failure | 辉瑞大药厂 | 2024-08-06 | — | — | CN | disclosed |