SCHEMBL31016355

SCHEMBL31016355

CCc1nc(C)oc1C(=O)Nc1nc2cc(C(N)=O)cc(OCCCN3CCOCC3)c2n1C/C=C/CN

nearest known ligand 0.72

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
STING1 Q86WV6 20/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22150062 0.92 STING1 (0.74) STING1
SCHEMBL22151431 0.92 STING1 (0.76) STING1
SCHEMBL31016325 0.90 STING1 (0.76) STING1
SCHEMBL22121625 0.90 STING1 (0.59) STING1
SCHEMBL22151433 0.88 STING1 (0.69) STING1
Trifluoroacetic Acid SCHEMBL31016342 0.88 STING1 (0.70) STING1
SCHEMBL22121423 0.88 STING1 (0.82) STING1
SCHEMBL22121426 0.88 STING1 (0.82) STING1
SCHEMBL22151663 0.88 STING1 (0.57) STING1
SCHEMBL22150059 0.88 STING1 (0.62) STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4673439-A1 STING AGONISTS CONTAINING HYDRAZIDE, HYDRAZINE, AND HYDROXAMIC ACID FUNCTIONAL GROUPS BioNTech SE (DE) 2026-01-07 EP disclosed
WO-2024182414-A1 STING AGONISTS CONTAINING HYDRAZIDE, HYDRAZINE, AND HYDROXAMIC ACID FUNCTIONAL GROUPS BIONTECH US INC. (US) 2024-09-06 WO disclosed