SCHEMBL22151663

SCHEMBL22151663

CCc1nc(C)oc1C(O)Nc1nc2cc(C(N)=O)cc(OCCCN3CCOCC3)c2n1C/C=C/CN

nearest known ligand 0.57

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
STING1 Q86WV6 20/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22121625 0.89 STING1 (0.59) STING1
SCHEMBL31016355 0.88 STING1 (0.72) STING1
SCHEMBL22150388 0.84 STING1 (0.71) STING1
SCHEMBL22136242 0.83 STING1 (0.53) STING1
SCHEMBL22121471 0.82 STING1 (0.57) STING1
SCHEMBL22121499 0.81 STING1 (0.63) STING1
SCHEMBL22150389 0.80 STING1 (0.77) STING1
SCHEMBL22150062 0.80 STING1 (0.74) STING1
SCHEMBL22151431 0.80 STING1 (0.76) STING1
SCHEMBL22121479 0.79 STING1 (0.72) STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020132582-A1 STING AGONISTS AND USES THEREOF NIMBUS TITAN, INC. (US) 2020-06-25 WO disclosed