SCHEMBL3101709

SCHEMBL3101709

COc1cccc(OP(O)O)c1OC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.45
TP53 P04637 4/20 0.43
MAPT P10636 3/20 0.43
CYP3A4 P08684 2/20 0.43
KDM4E B2RXH2 2/20 0.43
LMNA P02545 2/20 0.43
HPGD P15428 2/20 0.43
ALDH1A1 P00352 2/20 0.43
MAPK1 P28482 2/20 0.43
ALOX15 P16050 1/20 0.43
ALOX12 P18054 1/20 0.43
HSD17B10 Q99714 1/20 0.43
NFE2L2 Q16236 4/20 0.43
CA1 P00915 3/20 0.42
CA2 P00918 3/20 0.42
CA12 O43570 2/20 0.42
CA7 P43166 2/20 0.42
CA9 Q16790 2/20 0.42
CA14 Q9ULX7 2/20 0.42
CA4 P22748 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10941893 0.87 MAPT (0.41) SMN1; SMN2MAPTCYP3A4KDM4EHPGD
SCHEMBL3101703 0.83 SMN1; SMN2 (0.48) SMN1; SMN2TP53MAPTCYP3A4KDM4E
SCHEMBL151213 0.82 CA1 (0.61) SMN1; SMN2TP53MAPTCYP3A4KDM4E
SCHEMBL27753904 0.82 CA1 (0.61) SMN1; SMN2TP53MAPTCYP3A4KDM4E
SCHEMBL25434306 0.82 CA1 (0.61) SMN1; SMN2TP53MAPTCYP3A4KDM4E
SCHEMBL5507872 0.80 CA1 (0.62) SMN1; SMN2TP53MAPTCYP3A4KDM4E
Ammonia Solution, Strong SCHEMBL4268652 0.79 SMN1; SMN2 (0.58) SMN1; SMN2TP53MAPTCYP3A4KDM4E
Hydrochloric Acid SCHEMBL31658961 0.79 SMN1; SMN2 (0.58) SMN1; SMN2TP53MAPTCYP3A4KDM4E
SCHEMBL27731704 0.79 SMN1; SMN2 (0.58) SMN1; SMN2TP53MAPTCYP3A4KDM4E
Bromide SCHEMBL28158222 0.79 SMN1; SMN2 (0.58) SMN1; SMN2TP53MAPTCYP3A4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7803850-B2 Camphorquinone derivative having acylphosphine oxide group, photopolymerization initiator and photo/chemical polymerization initiator containing the same and hardenable composition containing the same KABUSHIKI KAISHA SHOFU (JP) 2010-09-28 US disclosed
US-20090105361-A1 Camphorquinone Derivative Having Acylphosphine Oxide Group, Photopolymerization Catalyst And Photo/Chemical Polymerization Catalyst Containing The Same And Hardenable Composition Contaning The Same KABUSHIKI KAISHA SHOFU 2009-04-23 US disclosed
EP-0097152-A4 POLYPHENYLENE ETHER PHOSPHITES. GEN ELECTRIC (US) 1984-04-17 EP disclosed
EP-0097152-A1 POLYPHENYLENE ETHER PHOSPHITES GENERAL ELECTRIC COMPANY (US) 1984-01-04 EP disclosed
WO-1983002117-A1 POLYPHENYLENE ETHER PHOSPHITES GEN ELECTRIC (US) 1983-06-23 WO disclosed
US-4340514-A RESINATES INTERSTAB CHEMICALS INC. (US) 1982-07-20 US disclosed
US-4067903-A Manufacture of arylamines BASF AKTIENGESELLSCHAFT (DT) 1978-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090105361-A1 Camphorquinone Derivative Having Acylphosphine Oxide Group, Photopolymerization Catalyst And Photo/Chemical Polymerization Catalyst Containing The Same And Hardenable Composition Contaning The Same POLQ, GAK, CAD SMN1; SMN2 4348/4885TP53 4193/4885MAPT 2361/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.