Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 13/20 | 0.85 |
| ▸ | ABL1 | P00519 | 7/20 | 0.75 |
| ▸ | SRC | P12931 | 6/20 | 0.75 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.75 |
| ▸ | EGFR | P00533 | 3/20 | 0.75 |
| ▸ | FYN | P06241 | 3/20 | 0.75 |
| ▸ | YES1 | P07947 | 3/20 | 0.75 |
| ▸ | LYN | P07948 | 3/20 | 0.75 |
| ▸ | HCK | P08631 | 3/20 | 0.75 |
| ▸ | KIT | P10721 | 3/20 | 0.75 |
| ▸ | BCR | P11274 | 3/20 | 0.75 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.75 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.75 |
| ▸ | FGR | P09769 | 2/20 | 0.75 |
| ▸ | JAK3 | P52333 | 2/20 | 0.75 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.75 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.75 |
| ▸ | SIK1 | P57059 | 2/20 | 0.66 |
| ▸ | SIK2 | Q9H0K1 | 2/20 | 0.66 |
| ▸ | SIK3 | Q9Y2K2 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1147077 | 1.00 | LCK (0.85) | LCKABL1SRCMAPK14EGFR | |
| Ammonia Solution, Strong SCHEMBL31017653 | 0.99 | LCK (0.84) | LCKABL1SRCMAPK14EGFR | |
| SCHEMBL31017685 | 0.93 | LCK (0.80) | LCKABL1SRCMAPK14EGFR | |
| SCHEMBL773124 | 0.92 | LCK (1.00) | LCKABL1SRCMAPK14EGFR | |
| SCHEMBL25737565 | 0.92 | LCK (0.87) | LCKABL1SRCMAPK14EGFR | |
| SCHEMBL31634947 | 0.92 | LCK (1.00) | LCKABL1SRCMAPK14EGFR | |
| SCHEMBL24535452 | 0.90 | LCK (0.83) | LCKABL1SRCMAPK14EGFR | |
| SCHEMBL8213695 | 0.89 | LCK (0.81) | LCKABL1SRCMAPK14EGFR | |
| SCHEMBL14067006 | 0.89 | LCK (0.81) | LCKABL1SRCMAPK14EGFR | |
| SCHEMBL1704678 | 0.89 | LCK (0.90) | LCKABL1SRCMAPK14EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4622947-A1 | ENAMINE N-OXIDE TOOLS FOR TARGET IDENTIFICATION APPLICATIONS | Dana-Farber Cancer Institute, Inc. (US) | 2025-10-01 | — | — | EP | disclosed |
| WO-2024112754-A1 | ENAMINE N-OXIDE TOOLS FOR TARGET IDENTIFICATION APPLICATIONS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-05-30 | — | — | WO | disclosed |