SCHEMBL31018366

SCHEMBL31018366

O=C1OC2(c3ccc(Br)cc3Oc3cc(Br)ccc32)c2cc(CNCCOCCOCCCCCCCl)ccc21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSTP1 P09211 1/20 0.37
CYP3A4 P08684 1/20 0.37
FTO Q9C0B1 3/20 0.34
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
MAPT P10636 2/20 0.34
HTT P42858 2/20 0.34
HPGD P15428 1/20 0.34
CYP2C19 P33261 1/20 0.34
RECQL P46063 1/20 0.34
BLM P54132 1/20 0.34
SMAD3 P84022 1/20 0.34
PRMT1 Q99873 1/20 0.34
ACE2 Q9BYF1 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
TTR P02766 1/20 0.33
USP2 O75604 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
NT5E P21589 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31018357 0.88 GSTP1 (0.39) GSTP1CYP3A4FTOMEN1KMT2A
SCHEMBL31018350 0.84 GSTP1 (0.38) GSTP1CYP3A4FTOMEN1KMT2A
SCHEMBL31018349 0.84 CYP3A4 (0.47) GSTP1CYP3A4FTOMEN1KMT2A
SCHEMBL24942496 0.83 NT5E (0.41) GSTP1CYP3A4FTOMEN1KMT2A
SCHEMBL30112575 0.83 NT5E (0.41) GSTP1CYP3A4FTOMEN1KMT2A
SCHEMBL31018342 0.77 GSTP1 (0.54) GSTP1CYP3A4FTOMEN1KMT2A
SCHEMBL20442415 0.76 GSTP1 (0.39) GSTP1CYP3A4FTOMEN1KMT2A
SCHEMBL31018355 0.74 GSTP1 (0.37) GSTP1CYP3A4FTOMEN1KMT2A
SCHEMBL31018347 0.74 GSTP1 (0.37) GSTP1CYP3A4FTOMEN1KMT2A
SCHEMBL30112828 0.74 GSTP1 (0.37) GSTP1CYP3A4FTOMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4655355-A1 PHOTOACTIVE FLUORESCENT COMPOUNDS AND USE THEREOF FOR LABELING OF PROTEINS Eikon Therapeutics, Inc. (US) 2025-12-03 EP disclosed
WO-2024159100-A1 PHOTOACTIVE FLUORESCENT COMPOUNDS AND USE THEREOF FOR LABELING OF PROTEINS EIKON THERAPEUTICS, INC. (US) 2024-08-02 WO disclosed