SCHEMBL31018342

SCHEMBL31018342

O=C1OC2(c3ccc(Br)cc3Oc3cc(Br)ccc32)c2cc(CCl)ccc21

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSTP1 P09211 1/20 0.54
FTO Q9C0B1 9/20 0.46
MAPT P10636 3/20 0.46
MEN1 O00255 2/20 0.46
HTT P42858 2/20 0.46
KMT2A Q03164 2/20 0.46
PRMT1 Q99873 2/20 0.46
HPGD P15428 2/20 0.46
CYP2C19 P33261 1/20 0.46
RECQL P46063 1/20 0.46
BLM P54132 1/20 0.46
SMAD3 P84022 1/20 0.46
ACE2 Q9BYF1 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
CYP3A4 P08684 1/20 0.44
LMNA P02545 2/20 0.40
ALDH1A1 P00352 2/20 0.40
USP2 O75604 1/20 0.40
OPRM1 P35372 1/20 0.38
OPRD1 P41143 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31018340 0.88 FTO (0.49) GSTP1FTOMAPTMEN1HTT
SCHEMBL3481392 0.82 FTO (0.50) GSTP1FTOMAPTMEN1HTT
SCHEMBL31018343 0.81 FTO (0.67) FTOMAPTMEN1HTTKMT2A
SCHEMBL31018357 0.80 GSTP1 (0.39) GSTP1FTOMAPTMEN1HTT
SCHEMBL13329826 0.80 FTO (0.69) FTOMAPTMEN1HTTKMT2A
SCHEMBL31159639 0.80 FTO (0.69) FTOMAPTMEN1HTTKMT2A
SCHEMBL1469054 0.78 GSTP1 (0.49) GSTP1FTOMAPTMEN1HTT
SCHEMBL22191880 0.78 FTO (0.71) FTOMAPTMEN1HTTKMT2A
SCHEMBL13058004 0.78 FTO (0.49) GSTP1FTOMAPTMEN1HTT
SCHEMBL31018366 0.77 GSTP1 (0.37) GSTP1FTOMAPTMEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4655355-A1 PHOTOACTIVE FLUORESCENT COMPOUNDS AND USE THEREOF FOR LABELING OF PROTEINS Eikon Therapeutics, Inc. (US) 2025-12-03 EP disclosed
WO-2024159100-A1 PHOTOACTIVE FLUORESCENT COMPOUNDS AND USE THEREOF FOR LABELING OF PROTEINS EIKON THERAPEUTICS, INC. (US) 2024-08-02 WO disclosed